Six meridians refers to Taiyang, Yangming, Shaoyang, Taiyin, Shaoyin, Jueyin terms. â€œShang Han Lunâ€ (â€œTreatise on Febrile Diseasesâ€) uses six meridians differentiation as the guiding principle. The six meridians concept was developed from â€œHuang Di Nei Jingâ€ plain question of heat topic. The concept and differentiation of six meridians in â€œShang Han Lunâ€ summarize the physiological function and pathological changes of zang-fu, meridians and qi-blood. And in accordance with the strength of the human body resistance to disease, attributes of pathogen, the advance and retreat priorities of the illness and other factors etc, doctors will analysis, integrate and summarize the various syndromes of exopathic disease, then discuss the site of disease, syndrome characteristics, zang-fu damaging, cold and heat trend, growth and decline of evil and zheng qi, as well as principle and prescription etc. "Treatise on Febrile Diseases" is not only the differentiation program, but also norms of treatment.